The Franco Lab is dedicated to understanding how the human genome functions and how its normal regulation breaks down in cancer. We study how genes are turned on and off, and how disruptions in these processes contribute to tumor development and progression. Our research focuses on the molecular mechanisms that control gene expression, with particular emphasis on the epigenome and non-coding RNAs; key regulators that shape when, where, and how genes are used.

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By combining genetic engineering, molecular biology, and bioinformatics, we take an interdisciplinary approach to uncover fundamental insights into cancer biology. Our goal is to translate these discoveries into new strategies for cancer prevention, diagnosis, and treatment.